Quantitative phase microscopy for the study of bone cells on multiple roughness surfaces

Jesús González-Laprea, Ana H. Márquez, Karem Noris-Suarez, Rafael Escalona

Producción científica: Capítulo del libro/informe/acta de congresoContribución de conferenciarevisión exhaustiva


We present a phase shifting interferometry system for the study of the early adhesion process for osteoblast-like cells, through an interference microscope. Optical phase maps from the cells are obtained experimentally as a function of cell adhesion time. The process is carried out on surfaces of metallic materials relevant to the development of bone implants. The surfaces were subjected to various levels of mechanical polishing and their roughness was measured using the same experimental technique mentioned before. Morphological changes of the cell can be measured over their optical phase maps while the cell adhesion process is accomplished. The experimental technique shows a suitable feature as to the observed time scale, and also shows a high stockiness and precision for the determination of the optical phase.

Idioma originalInglés
Título de la publicación alojadaInterferometry XVI
Subtítulo de la publicación alojadaApplications
EstadoPublicada - 2012
Publicado de forma externa
EventoInterferometry XVI: Applications - San Diego, CA, Estados Unidos
Duración: 13 ago. 201216 ago. 2012

Serie de la publicación

NombreProceedings of SPIE - The International Society for Optical Engineering
ISSN (versión impresa)0277-786X


ConferenciaInterferometry XVI: Applications
País/TerritorioEstados Unidos
CiudadSan Diego, CA

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