Resumen
Thirty-seven patients with essential tremor were given intramuscular clonidine injections of 0.3 mg. Physical examination and statistical analysis showed that response was highly positive (t = 13.47; p < 0.0001) 60 min after administration. The absence of peripheral α-adrenergic receptors for tremor suggest that the drug acts centrally, consistent with the theory that essential tremor originates in a central oscillating pacemaker.
Título traducido de la contribución | Clonidine acute pharmacologic test in essential tremor |
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Idioma original | Español |
Páginas (desde-hasta) | 9-11 |
Número de páginas | 3 |
Publicación | Neurologia |
Volumen | 12 |
N.º | 1 |
Estado | Publicada - ene. 1997 |
Publicado de forma externa | Sí |
Palabras clave
- α receptors for tremor
- clonidine
- essential tremor