TY - JOUR
T1 - COVID 19 IN PREGNANT WOMEN AND NEONATES: CLINICAL CHARACTERISTICS AND LABORATORY AND IMAGING FINDINGS. AN OVERVIEW OF SYSTEMATIC REVIEWS
AU - VERDESOTO JACOME, CATALINA ANGELICA
PY - 2022/3/25
Y1 - 2022/3/25
N2 - Febrile neutropenia is a common and serious complication of cancer chemotherapy. This pathology is characterized by a diminished absolute neutrophil count and elevated temperature. Despite recent therapeutic advances, febrile neutropenia is still a major cause of morbidity and mortality among cancer patients in Latin America and worldwide. This onco-hematological emergency condition also involves a high risk of complications and healthcare costs. The objective of this protocol was to develop a reference tool for the evaluation and management of febrile neutropenia in a fourth-level cancer hospital in Ecuador and provide a guideline for a timely and adequate care of cancer patients. The present project implemented an extensive bibliographic search of the last 15 y which included guidelines and scientific publications. The appraisal of guidelines for research and evaluation II and grading of recommendations, assessment, development and evaluation instruments were used to develop an expert consensus and evaluate the level of evidence of each recommendation. This document compiles updated information available on the definition, risk factors, evaluation methods, treatment and special situations in cancer patients with febrile neutropenia. Moreover, the following report allows to classify patients according to their risk level and to provide the best pharmacological strategy with their respective doses and routes of administration. Cytotoxic chemotherapy often induces febrile neutropenia and may lead to serious complications including mortality. Therefore, information available on febrile neutropenia was compiled to create a comprehensive protocol of the complication.
AB - Febrile neutropenia is a common and serious complication of cancer chemotherapy. This pathology is characterized by a diminished absolute neutrophil count and elevated temperature. Despite recent therapeutic advances, febrile neutropenia is still a major cause of morbidity and mortality among cancer patients in Latin America and worldwide. This onco-hematological emergency condition also involves a high risk of complications and healthcare costs. The objective of this protocol was to develop a reference tool for the evaluation and management of febrile neutropenia in a fourth-level cancer hospital in Ecuador and provide a guideline for a timely and adequate care of cancer patients. The present project implemented an extensive bibliographic search of the last 15 y which included guidelines and scientific publications. The appraisal of guidelines for research and evaluation II and grading of recommendations, assessment, development and evaluation instruments were used to develop an expert consensus and evaluate the level of evidence of each recommendation. This document compiles updated information available on the definition, risk factors, evaluation methods, treatment and special situations in cancer patients with febrile neutropenia. Moreover, the following report allows to classify patients according to their risk level and to provide the best pharmacological strategy with their respective doses and routes of administration. Cytotoxic chemotherapy often induces febrile neutropenia and may lead to serious complications including mortality. Therefore, information available on febrile neutropenia was compiled to create a comprehensive protocol of the complication.
UR - https://revistas.unal.edu.co/index.php/revfacmed/article/view/97588
M3 - Artículo
SN - 0120-0011
JO - Revista Facultad de Medicina
JF - Revista Facultad de Medicina
ER -