TY - JOUR
T1 - The clinical impression of severity index for Parkinson's disease
T2 - International validation study
AU - Martínez-Martín, Pablo
AU - Rodríguez-Blázquez, Carmen
AU - Forjaz, Maria João
AU - de Pedro, Jesús
AU - Aguilar, M.
AU - Álvarez Saúco, M.
AU - Bayés, A.
AU - Blázquez, M.
AU - Bergareche, A.
AU - Campos, V.
AU - Carballo, M.
AU - Catalán, M. J.
AU - Chacón, J.
AU - Cubo, E.
AU - Fernández-García, J. M.
AU - LInazasoro, G.
AU - López del Val, J.
AU - Martínez-Castrillo, J. C.
AU - Mendoza, A.
AU - Mir, P.
AU - Kulisevsky, J.
AU - Valldeoriola, F.
AU - Vela, L.
AU - Vivancos, F.
AU - Virués, J.
AU - Arroyo, S.
AU - Frades, B.
AU - Carod-Artal, F. J.
AU - Micheli, F.
AU - Serrano-Dueñas, M.
AU - Galeano, G.
AU - Meza-Rojas, G.
AU - Velázquez, C.
PY - 2009/1/30
Y1 - 2009/1/30
N2 - This study sought to provide further information about the psychometric properties of the Clinical Impression of Severity Index for Parkinson's Disease (CISI-PD), in a large, international, cross-culturally diverse sample. Six hundred and fourteen patients with PD participated in the study. Apart from the CISI-PD, assessments were based on Hoehn & Yahr (HY) staging, the Scales for Outcomes in PD-Motor (SCOPA-M), -Cognition (SCOPA-COG) and -Psychosocial (SCOPA-PS), the Cumulative Illness Rating Scale-Geriatrics, and the Hospital Anxiety and Depression Scale. The total CISI-PD score displayed no floor or ceiling effects. Internal consistency was 0.81, the test-retest intraclass correlation coefficient was 0.84, and item homogeneity was 0.52. Exploratory and confirmatory factor analysis (CFI = 0.99, RMSEA = 0.07) confirmed CISI-PD's unifactorial structure. The CISI-PD showed adequate convergent validity with SCOPA-COG and SCOPA-M (r S = 0.46-0.85, respectively) and discriminative validity for HY stages and disease duration (P < 0.0001). In a multiple regression model, main CISI-PD predictors were SCOPA-M, disease duration, and depression. The results obtained were not only comparable to but also extended those yielded by the preliminary validation study, thus showing that the CISI-PD is a valid instrument to measure clinical impression of severity in PD. Its simplicity and easy application make it an attractive and useful tool for clinical practice and research.
AB - This study sought to provide further information about the psychometric properties of the Clinical Impression of Severity Index for Parkinson's Disease (CISI-PD), in a large, international, cross-culturally diverse sample. Six hundred and fourteen patients with PD participated in the study. Apart from the CISI-PD, assessments were based on Hoehn & Yahr (HY) staging, the Scales for Outcomes in PD-Motor (SCOPA-M), -Cognition (SCOPA-COG) and -Psychosocial (SCOPA-PS), the Cumulative Illness Rating Scale-Geriatrics, and the Hospital Anxiety and Depression Scale. The total CISI-PD score displayed no floor or ceiling effects. Internal consistency was 0.81, the test-retest intraclass correlation coefficient was 0.84, and item homogeneity was 0.52. Exploratory and confirmatory factor analysis (CFI = 0.99, RMSEA = 0.07) confirmed CISI-PD's unifactorial structure. The CISI-PD showed adequate convergent validity with SCOPA-COG and SCOPA-M (r S = 0.46-0.85, respectively) and discriminative validity for HY stages and disease duration (P < 0.0001). In a multiple regression model, main CISI-PD predictors were SCOPA-M, disease duration, and depression. The results obtained were not only comparable to but also extended those yielded by the preliminary validation study, thus showing that the CISI-PD is a valid instrument to measure clinical impression of severity in PD. Its simplicity and easy application make it an attractive and useful tool for clinical practice and research.
KW - Assessment
KW - Clinical impression of severity index
KW - Global impression of severity
KW - Parkinson's disease
KW - Rating scales
UR - https://www.scopus.com/pages/publications/61649085932
U2 - 10.1002/mds.22320
DO - 10.1002/mds.22320
M3 - Article
C2 - 18973256
AN - SCOPUS:61649085932
SN - 0885-3185
VL - 24
SP - 211
EP - 217
JO - Movement Disorders
JF - Movement Disorders
IS - 2
ER -